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| Melo,Mônica S; Guimarães,Adriana G; Santana,Michele F; Siqueira,Rosana S; De Lima,Amanda Do Carmo B; Dias,Antonio S; Santos,Márcio Roberto V; Onofre,Alexandre S.C.; Quintans,Jullyana S.S.; De Sousa,Damião P; Almeida,Jackson R.G.S.; Estevam,Charles S; Araujo,Brancilene S; Quintans-Júnior,Lucindo J. |
| The anti-inflammatory and redox protective effects of the citronellal (CT) were evaluated using in vivo and in vitro tests. Intraperitoneal (i.p.) administration of CT (50, 100, and 200 mg/kg) inhibited (p < 0.05) the carrageenan-induced leukocyte migration to the peritoneal cavity. Additionally, the carrageenan- and arachidonic acid-induced rat hind paw edema was significantly inhibited (p < 0.05) by i.p. administration of 100 and 200 mg/kg of the compound. When the redox activity was evaluated, CT (200 mg/kg) significantly reduced hepatic lipoperoxidation (p < 0.001), as well as oxidation of plasmatic (p < 0.05) and hepatic (p < 0.01) proteins. The results of the present study support the hypothesis that CT possesses anti-inflammatory and... |
| Tipo: Journal article |
Palavras-chave: Monoterpene; Citronellal; Anti-inflammatory; Redox. |
| Ano: 2011 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602011000400008 |
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| Barros,L.A.; Yamanaka,A.R.; Silva,L.E.; Vanzeler,M.L.A.; Braum,D.T.; Bonaldo,J.. |
| Human infection with fish parasites can result from the ingestion of incompletely cooked or raw fish, giving origin to parasitic diseases such as anisakiasis, caused by parasites of the Anisakidae family. The present study assessed the in vitro larvicidal effect of two monoterpene compounds, geraniol and citronellal, against Contracaecum sp (Nematoda: Anisakidae). Four hundred live larvae of Contracaecum sp obtained from "traíra" fish (Hoplias malabaricus, Bloch, 1974) were analyzed on 40 Petri dishes (10 larvae each) with the compounds to be tested. The final concentrations tested for each compound were 250, 125, 62.5, and 31.2 µg/mL and the evaluation was carried out at five different times (2, 4, 8, 24, and 48 h). The larvicidal action of geraniol and... |
| Tipo: Info:eu-repo/semantics/other |
Palavras-chave: Geraniol; Citronellal; Larvicide; Contracaecum sp. |
| Ano: 2009 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2009001000007 |
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